A hidden step before meiosis could reshape efforts to treat infertility
Phys.org
February 20, 2026
AI-Generated Deep Dive Summary
A groundbreaking discovery has revealed a previously unknown step in the process of epigenetic reprogramming during meiosis, which could revolutionize efforts to treat infertility. In human cells, DNA is marked with chemical tags known as "epigenetic" marks that regulate gene expression across different tissues. However, in germ cells—specialized cells destined to become sperm and eggs—these inherited instructions must be erased or reshuffled to allow for fresh development in future generations.
This critical process of erasing epigenetic memory occurs during meiosis, the phase of cell division that produces gametes. The discovery highlights a hidden mechanism by which these specialized cells reset their genetic programming, ensuring that each new organism starts with a clean slate. This reprogramming involves complex molecular processes, including DNA methylation and histone modification, which scientists are now beginning to unravel in greater detail.
Understanding this hidden step could open up new avenues for infertility treatments. By targeting the
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Originally published on Phys.org on 2/20/2026