A new 'molecular switch' for inborn immunity identified

Phys.org

March 6, 2026

Innate immune sensors—known as pattern recognition receptors (PRRs)—detect specific molecular components of bacterial or viral intruders. The PRRs forward the signals which results in the production of interferons, which in turn guide the immune cells. However, until now the precise mechanism of how these signals are forwarded has remained enigmatic.