AAOS: GLP-1 receptor agonist use increases five-year risk for osteoporosis

Medical Xpress
March 7, 2026
Treatment with glucagon-like peptide-1 receptor agonists (GLP-1 RAs) for type 2 diabetes and obesity is independently associated with a significantly increased five-year risk for osteoporosis, gout, and osteomalacia compared with nonuse, according to a study presented at the annual meeting of the American Academy of Orthopaedic Surgeons, held from March 2 to 6 in New Orleans.
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Originally published on Medical Xpress on 3/7/2026