Atom-sized gates could transform DNA sequencing and neuromorphic computing
Science Daily
February 19, 2026
AI-Generated Deep Dive Summary
Scientists have made a groundbreaking advancement in creating atom-sized pores that mimic biological ion channels, potentially revolutionizing fields like DNA sequencing and neuromorphic computing. By employing a mini electrochemical reactor on a silicon nitride membrane, researchers successfully generated subnanometer pores—just a few atoms wide—that can be opened and closed hundreds of times, demonstrating remarkable durability and control. This innovative process involves applying a negative voltage to trigger a chemical reaction that forms a solid precipitate, blocking the pore, which dissolves upon reversing the voltage.
The research draws inspiration from nature's ion channels, which regulate ion movement in cells by opening or closing based on external signals. By monitoring ion current spikes through the membrane, the team observed patterns consistent with the formation of numerous ultrasmall pores. They also discovered that adjusting the chemical composition and pH of reactants allowed them to fine-tune pore size and properties, enabling selective ion transport.
This breakthrough offers a novel approach to studying fluid and ion movement at scales comparable to living systems. Beyond fundamental research, the technology holds promise for applications in single-molecule sensing, such as DNA sequencing, and neuromorphic computing, where electrical spikes can mimic biological neurons. By replicating nature's precision on an atomic scale, this innovation could pave the way for transformative advancements in science and technology.
Verticals
scienceresearch
Originally published on Science Daily on 2/19/2026