Clearing trapped cholesterol could relieve lymphoedema

Nature

by Babak Mehrara

February 13, 2026

Impaired lymphatic function causes cholesterol to accumulate in tissues, driving swelling known as lymphoedema. Lipid clearance could be an effective therapeutic strategy. Impaired lymphatic function causes cholesterol to accumulate in tissues, driving swelling known as lymphoedema. Lipid clearance could be an effective therapeutic strategy.

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Originally published on Nature on 2/13/2026