Cloaked stem cells evade immune rejection in mice, pointing to a potential universal donor cell line
Medical Xpress
March 5, 2026
A study published in Stem Cell Reports demonstrates that genetically engineered human pluripotent stem cells (hPSCs) can overcome immune rejection in mice with humanized immune systems, surviving for five months in a stringent transplantation model. The findings provide proof-of-principle for the development of a potential universal donor hPSC line designed to resist immune attack.
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Originally published on Medical Xpress on 3/5/2026