Daily briefing: This Utah family line might be evidence of ‘selfish genes’ in humans

Nature

by Flora Graham

March 2, 2026

AI-Generated Deep Dive Summary

Researchers have discovered a Utah family where seven generations show twice as many boys as girls, suggesting the presence of genes that distort sex ratios. This finding, detailed in a study published on bioRxiv, marks the first conclusive evidence of such "selfish" genes in humans. Evolutionary geneticist James Baldwin-Brown highlights the strong signal from this family's data, indicating a potential genetic mechanism favoring male offspring. However, some researchers remain cautious, urging further investigation to rule out alternative explanations. In another breakthrough, stem cells applied directly to fetuses with spina bifida during utero have shown promise in reversing complications. A small trial involving six pregnant women found the treatment safe and effective in addressing cerebrospinal fluid circulation issues. While long-term benefits are still uncertain, this approach offers hope for treating this severe birth defect, potentially improving outcomes for affected infants. Additionally, a study on "super agers"—individuals over 80 with exceptional memory—reveals they produce significantly more new neurons than others, including those with Alzheimer's. This finding supports the idea that adult brains continue generating neurons and could pave the way for drugs targeting neurogenesis to treat cognitive decline. Finally, the 30th anniversary of Pokémon highlights its surprising influence on science. Researchers have drawn inspiration from the franchise in fields like ecology, evolution, and education, even naming new species after Pokémon characters. This connection underscores how pop culture can inspire scientific curiosity and innovation across disciplines. These discoveries collectively emphasize the dynamic interplay between genetics, stem cell research, cognitive health, and unexpected cultural influences on science. Each breakthrough not only advances its specific field but also highlights the broader impact of scientific exploration on society and human well-being.

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Originally published on Nature on 3/2/2026