Duke vs. Clemson odds, prediction, time: 2026 college basketball picks for February 14 from proven model

CBS Sports
by Daniel Kohn
February 14, 2026
AI-Generated Deep Dive Summary
Duke vs. Clemson odds, prediction, time: 2026 college basketball picks for February 14 from proven model
Two of the Atlantic Coast Conference's top teams, the No. 20 Clemson Tigers and the fourth-ranked Duke Blue Devils, are set to clash in a highly anticipated matchup on February 14. This game pits Clemson (20-5, 10-2 ACC), currently tied with Virginia for second place in the conference, against Duke (22-2, 11-1 ACC), who lead the ACC standings and have an impressive 11-0 home record this season. The Tigers are strong on the road with a 6-2 record, while the Blue Devils dominate at their Cameron Indoor Stadium in Durham, N.C., where tipoff is scheduled for noon ET. The game carries significant historical weight, as Duke leads the all-time series 115-34. However, Clemson has managed to win two of the last three encounters, showcasing their ability to compete with the Blue Devils. In this matchup, injuries may play a role: Clemson's Zac Foster (knee) and Duke's Ifeanyi Ufochukwu (undisclosed) are both expected to miss the game, potentially impacting their respective teams' strategies. SportsLine's Projection Model has simulated this game 10,000 times and offers valuable insights for bettors. The model predicts that the Over/Under of 133.5 points is likely to hit, as it has occurred in five of the last 10 head-to-head meetings between these teams. Additionally, Duke is a strong favorite with a 13.5-point spread, reflecting their home-court advantage and overall dominance this season. The model also highlights key players who could impact the game. For Clemson, Jestin Porter is projected to score 12.2 points, while Cameron Boozer is expected to lead Duke with 21.8 points. The Blue Devils' strong performance at
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Originally published on CBS Sports on 2/14/2026