Duke vs. Michigan prediction, pick, odds, spread: No. 3 Blue Devils, No. 1 Wolverines meet in marquee showdown

CBS Sports
by Cameron Salerno
February 20, 2026
AI-Generated Deep Dive Summary
Duke vs. Michigan prediction, pick, odds, spread: No. 3 Blue Devils, No. 1 Wolverines meet in marquee showdown
A highly anticipated showdown between No. 1 Michigan and No. 3 Duke is set to take place on Saturday, with significant stakes for both teams. This nonconference game could shape the AP Top 25 rankings and influence the positioning for the NCAA Tournament's top seed. Both teams enter the game with strong records, as Michigan has won 11 straight games following a loss to Wisconsin, while Duke remains competitive despite setbacks against North Carolina and Texas Tech. The game is not only a clash of two elite programs but also features contrasting strengths that will determine the outcome. Michigan boasts one of the nation's best frontcourts, led by Morez Johnson Jr., Yaxel Lendeborg, and Aday Mara, who are tasked with containing Duke's standout big man, Cameron Boozer. Boozer has been a consistent force this season, earning national player of the year recognition. On the other side, Duke's guards, including Isaiah Evans, will need to step up against Michigan's backcourt duo of Elliot Cadeau and Nimari Burnett. The game's impact extends beyond the court, as it could set the stage for the NCAA Tournament bracket. The winner may secure a strong position for the No. 1 seed, while also potentially previewing a national title matchup if both teams advance far in the tournament. With both teams ranked highly in defensive efficiency and 3-point shooting, the game promises to be a tactical masterclass. For sports fans, this is a rare opportunity to witness two powerhouse programs collide in a nonconference game with playoff-level intensity. The outcome will not only define the immediate future of these teams but also set the tone for the rest of the season and beyond.
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Originally published on CBS Sports on 2/20/2026