Eric Dane, ‘Grey’s Anatomy’ And ‘Euphoria’ Star, Dies At 53

Forbes Business

by Marc Berman, Senior Contributor

February 20, 2026

AI-Generated Deep Dive Summary

Eric Dane, the actor best known for portraying Dr. Mark “McSteamy” Sloan on *Grey’s Anatomy* and his recent role in HBO’s *Euphoria*, has passed away at the age of 53 after a long battle with ALS (Amyotrophic Lateral Sclerosis). His death marks a significant loss for both the entertainment industry and fans worldwide, as he was a beloved figure known for his iconic performances on popular TV shows. This news not only sheds light on the challenges faced by individuals battling rare diseases like ALS but also underscores the impact of Eric Dane’s career on global audiences. Dane first gained widespread recognition for his role as Dr. Mark Sloan in *Grey’s Anatomy*, where he played a memorable and often controversial character known for his sharp wit and emotional depth. His portrayal earned him a dedicated fan base and solidified his status as one of the show’s key actors during its earlier seasons. After leaving *Grey’s Anatomy*, Dane transitioned to other roles, including appearances in *Euphoria* and various films, showcasing his versatility as an actor. Beyond his acting career, he was also known for his philanthropic efforts, particularly raising awareness for ALS following his diagnosis. Eric Dane’s passing highlights the broader implications of ALS, a debilitating neurodegenerative disease that affects muscle strength and movement. His openness about his battle with ALS brought attention to the challenges faced by those living with the disease and inspired further discussions around funding for research and treatment options. For fans of *Grey’s Anatomy* and *Euphoria*, his death is a profound loss, but it also serves as a reminder of the importance of supporting causes that aim to improve lives, such as ALS awareness campaigns. From a business perspective, Eric Dane’s legacy extends beyond entertainment, as his life story and career choices resonate with themes of resilience, perseverance, and the power of storytelling. His journey reflects how personal struggles can inspire broader societal change, particularly in areas like healthcare and philanthropy. As industries continue to prioritize social responsibility and awareness, Eric Dane’s example serves as a testament to the impact individuals can have, even after their passing.

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Originally published on Forbes Business on 2/20/2026