Eric Dane, McSteamy on ‘Grey’s Anatomy,’ Dies at 53 After Battling ALS

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by Johnny Diaz

February 20, 2026

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Eric Dane, the actor best known for his role as Dr. Mark Sloan, nicknamed McSteamy, on *Grey’s Anatomy*, has passed away at the age of 53 after a ten-month battle with ALS (Amyotrophic Lateral Sclerosis), also known as Lou Gehrig’s disease. Diagnosed in April 2025, Dane courageously shared his experience with the debilitating neurological condition through interviews and social media, raising awareness for ALS research and patient advocacy. Dane’s career skyrocketed in 2006 when he joined *Grey’s Anatomy* as the charming plastic surgeon Dr. Mark Sloan. His character became a fan favorite due to his magnetic personality and iconic monologues, earning him widespread recognition and acclaim in the entertainment industry. Beyond television, he appeared in numerous films and stage productions, showcasing his talent as both an actor and a theater producer. In his later years, Dane focused on advocating for ALS awareness, even participating in campaigns to raise funds and promote research. His death, confirmed by publicist Melissa Bank, occurred while surrounded by his family, including his wife and two daughters, Billie and Georgia. He had previously expressed how the disease impacted his daily life, describing the gradual loss of muscle control and speech as both a challenge and a reminder of the importance of continuing the fight against ALS. Dane’s passing is significant not only for fans of *Grey’s Anatomy* but also for those interested in medical advancements and patient advocacy. His openness about his battle with ALS inspired many to support research efforts and highlighted the ongoing struggles faced by individuals living with the disease. As a beloved figure in pop culture, his legacy will continue to influence both entertainment and the fight against neurological disorders.

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Originally published on NYT Homepage on 2/20/2026