Grey's Anatomy star Eric Dane dies at 53 after ALS diagnosis
BBC World
February 20, 2026
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Actor Eric Dane, best known for his roles as Dr. Mark Sloan on *Grey's Anatomy* and Cal Jacobs on *Euphoria*, has passed away at the age of 53 after a brave battle with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease. Diagnosed in April 2023, Dane spent his final year raising awareness for this rare and devastating condition, which causes progressive muscle weakness and eventual loss of movement, speech, and breathing abilities. His family shared a heartfelt statement confirming his passing, emphasizing that he was surrounded by loved ones during his last days, including his wife Rebecca Gayheart and their two daughters, Billie and Georgia.
Dane's career spanned over three decades, with notable roles in *Grey's Anatomy*, where he joined the main cast as Dr. Mark Sloan in 2006, and *Euphoria*, where he played the family patriarch Cal Jacobs starting in 2021. He also appeared in other projects, including *The Last Ship*, *Charmed*, and films like *Marley & Me*. Beyond his professional achievements, Dane was deeply cherished by fans for his humor, charm, and ability to connect with audiences. His co-stars and colleagues paid tribute to him, highlighting his impact on their lives and the entertainment industry.
ALS is a rare neurodegenerative disease that affects motor neurons, leading to progressive paralysis and loss of muscle control. Dane's personal struggle with ALS added an emotional layer to his legacy, as he openly shared his experiences with the disease to raise awareness. His poignant reflection on his father's suicide at age seven, which left him without a father figure, resonated with many who admired his strength in facing life's challenges. His passing has deeply saddened
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Originally published on BBC World on 2/20/2026