Herpes simplex virus liquefies cell nuclei to build viral 'factories'

Medical Xpress
March 5, 2026
Herpes simplex virus partially liquefies the tightly packed, gel-like interior of human cell nuclei to copy itself faster, a new study shows. The research centers on how the nucleus of each human cell houses the genetic machinery used to copy DNA-encoded instructions when it divides and multiplies as part of growth. Viruses invade human cells and use their machinery to copy themselves, but the invasion can be hindered by the dense structure of the nucleus.
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Originally published on Medical Xpress on 3/5/2026