Just three molecules can launch gene-silencing condensates in stem cells
Phys.org
March 4, 2026
A new study has uncovered how an exceptionally scarce protein can orchestrate the assembly of large-scale gene-silencing structures inside cells, and what happens when that process breaks down. The findings, published today in Molecular Cell, identify a self-clustering mechanism in the Polycomb protein CBX2 that is essential for initiating the formation of gene-repressive condensates and guiding stem cells toward their proper fates.
Verticals
sciencephysics
Originally published on Phys.org on 3/4/2026