Leader of Columbia Brain Institute Quits Over Friendship With Epstein

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by Sharon Otterman

February 25, 2026

AI-Generated Deep Dive Summary

Nobel laureate Richard Axel has resigned as co-director of the Mortimer B. Zuckerman Mind Brain Behavior Institute at Columbia University following his admitted association with Jeffrey Epstein. Though Axel is not accused of wrongdoing, he acknowledged that his friendship with Epstein—a convicted sex offender—constituted a "serious error in judgment." The resignation stems from the release of millions of pages of Epstein's private files, which revealed continued connections with influential figures, including academics and philanthropists, despite his 2008 felony convictions for solicitation of prostitution by a minor. Axel’s ties to Epstein were detailed in the documents, showing that he was a frequent guest at Epstein’s Manhattan home and acted as an intermediary between Epstein and Columbia University officials regarding admissions and philanthropic efforts. In a statement, Axel expressed deep regret for compromising the trust of his colleagues, students, and friends, emphasizing the pain caused by Epstein's appalling conduct. This marks the latest in a series of repercussions for academia linked to Epstein’s relationships with powerful individuals. The fallout underscores the broader impact of Epstein’s connections on the scientific and academic communities. As more details emerge about his interactions with influential figures, questions arise about the ethical implications of such associations and their potential consequences. Axel’s resignation highlights the ongoing scrutiny faced by those linked to Epstein, even in cases where no direct wrongdoing is alleged. This story matters because it reflects the delicate balance between personal relationships and professional ethics, particularly in high-stakes academic environments. It also sheds light on the broader societal concerns about power dynamics and accountability, especially when individuals in positions of influence are involved. The case serves as a cautionary tale about the potential consequences of associating with figures like Epstein, whose actions have had far-reaching effects across multiple industries. In a world where trust is critical to maintaining credibility, Axel’s decision to step down sends a strong message about the importance of accountability and integrity in leadership roles. As investigations and revelations continue to surface, this case will likely remain a significant topic of discussion for those interested in understanding the intersection of power, ethics, and reputation in academia and beyond.

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Originally published on NYT Homepage on 2/25/2026