Low-dose lithium may slow verbal memory decline, exploratory clinical trial suggests
Medical Xpress
March 2, 2026
Lithium—a decades-old treatment for bipolar disorder—may hold potential neuroprotective benefits beyond mood stabilization. An exploratory clinical trial from the University of Pittsburgh suggests that low-dose oral lithium may help slow the decline of verbal memory, or ability to remember and recall words and sentences, in older adults with mild cognitive impairment, particularly among those with evidence of amyloid beta—one of the hallmark biomarkers of Alzheimer's disease.
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Originally published on Medical Xpress on 3/2/2026