Menopause, hormones and the brain: How hormone therapy could help protect against Alzheimer's
Medical Xpress
February 14, 2026
AI-Generated Deep Dive Summary
As dementia and neurodegenerative diseases become increasingly prevalent, researchers are exploring innovative ways to protect brain health as we age. One promising area of focus is the role of hormones, particularly during menopause and its aftermath. Emerging evidence suggests that hormone therapy could play a significant role in reducing the risk of Alzheimer's disease by addressing hormonal imbalances linked to cognitive decline.
The transition through menopause brings about a sharp decline in estrogen levels, which can have far-reaching effects on brain function. Estrogen is known to support neural health by promoting blood flow, protecting neurons, and enhancing memory formation. Studies indicate that women who undergo early menopause or experience prolonged hormonal changes are more susceptible to cognitive impairments later in life. This connection between hormonal shifts and neurodegenerative diseases has sparked renewed interest in hormone therapy as a potential protective measure.
Hormone therapy during menopause involves补充雌激素或其他相关激素以缓解更年期症状并维持身体功能。Recent research suggests that timely and appropriate hormone replacement may help preserve cognitive function by mitigating the negative effects of estrogen loss. For instance, some studies have shown that women who use hormone therapy exhibit better memory retention and a lower risk of developing Alzheimer's compared to those who do not. These findings highlight the potential benefits of hormone therapy as a proactive approach to brain health.
The implications of this research are particularly significant for women seeking ways to safeguard their cognitive well-being as they age. Alzheimer's disease, the most common form of
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Originally published on Medical Xpress on 2/14/2026