Michigan vs. Duke odds, prediction, time: 2026 college basketball picks for Feb. 21 from proven model

CBS Sports
by Daniel Lewis
February 21, 2026
AI-Generated Deep Dive Summary
Michigan vs. Duke odds, prediction, time: 2026 college basketball picks for Feb. 21 from proven model
The highly anticipated college basketball showdown between the No. 1 Michigan Wolverines and the No. 3 Duke Blue Devils is set for Feb. 21 in Washington D.C., part of the 2026 Edward Jones Capital Showcase. This game features two top-tier programs, both projected as likely No. 1 seeds in the NCAA Tournament. Michigan enters with a stellar 25-1 record, while Duke boasts a 24-2 mark, making this matchup one of the most significant non-conference games of the season. The Wolverines’ balanced offensive attack, highlighted by five players averaging at least 10 points per game and led by Yaxell Lendeborg’s 14.4 points per contest, has them ranked first in the nation with an average of 90.6 points per game. On the other hand, Duke relies heavily on freshman Cameron Boozer, who averages a impressive 22.8 points per game, propelling the Blue Devils to an 83-point-per-game average. SportsLine’s Projection Model has simulated this clash over 10,000 times, predicting a high-scoring affair with a projected total of 15
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Originally published on CBS Sports on 2/21/2026