Q&A: Algorithm achieves near end-to-end genome assembly without ultra-long DNA sequencing
Phys.org
February 16, 2026
Haoyu Cheng, Ph.D., assistant professor of biomedical informatics and data science at Yale School of Medicine, has developed a new algorithm capable of building complete human genomes using standard laboratory technology. His tool, called hifiasm (ONT), eliminates the need for costly DNA sequencing that requires 40 times more genetic material and often cannot be performed on patient samples.
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Originally published on Phys.org on 2/16/2026