Synthetic gene medicines may disrupt DNA repair
Phys.org
March 3, 2026
Antisense oligonucleotides (ASOs), used to treat genetic diseases, can affect how cells repair damage to their DNA. This is shown in a new study from Karolinska Institutet, published in Nature Communications. The findings may have implications for the development of future genetic medicines and deepen our understanding of how RNA, natural counterparts to ASOs, participate in DNA repair systems.
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Originally published on Phys.org on 3/3/2026