Thunder vs. Pistons odds, prediction, spread, time: 2026 NBA picks for Wednesday, Feb. 25 from proven model

CBS Sports
by Daniel Kohn
February 25, 2026
AI-Generated Deep Dive Summary
Thunder vs. Pistons odds, prediction, spread, time: 2026 NBA picks for Wednesday, Feb. 25 from proven model
The Oklahoma City Thunder aim to extend their winning streak as they face the Detroit Pistons in a highly anticipated NBA clash on Wednesday, February 25. Both teams are performing exceptionally this season, with the Thunder boasting a strong 45-14 record and excelling on the road at 21-7, while the Pistons maintain a solid 42-14 record and have proven formidable at home with a 21-7 mark in their own arena. The game features key matchups, including the Thunder's balanced lineup, despite injuries to Shai Gilgeous-Alexander (abdominal), Jalen Williams (hamstring), and Isaiah Hartenstein (calf), as well as the Pistons' star Cade Cunningham, who is expected to play a pivotal role. SportsLine's Projection Model has simulated this matchup 10,000 times and predicts a close contest, with Detroit favored by 10.5 points. The model highlights the Pistons' likelihood of winning outright but also notes that the total points scored could fall short of the over/under line of 219.5, as both teams have shown tendencies to keep games low at times. Additionally, the model projects Cade Cunningham to be the leading scorer with 24.6 points for Detroit, while Oklahoma City's top players are expected to stay below 15 points each. The matchup is crucial for both teams' playoff positioning and offers significant implications for bettors. The Thunder will look to maintain their momentum against a strong Pistons team, which has been dominant at home this season. With the model favoring Detroit but also pointing towards an under in total points, fans and bettors should consider the trend of low-scoring games in Pistons' home contests this season. This game is not just about the on-court action; it's also a key moment for NBA enthusiasts to test their predictions against SportsLine's proven model. The model has consistently delivered profitable picks, making it a reliable source for sports betting advice. As the game approaches, fans can expect an intense battle between two competitive teams, with potential upsets and close scores adding to the excitement. For those looking to enhance their betting strategy or simply follow the NBA action closely, staying informed with accurate predictions and insights is crucial. Whether you're a die-hard fan or a casual sports enthusiast, this matchup promises to deliver drama and strategic depth, making it a must-watch
Verticals
sports
Originally published on CBS Sports on 2/25/2026