Video: Using combined therapy to treat obesity

Medical Xpress
February 20, 2026
AI-Generated Deep Dive Summary
Recent research highlights the effectiveness of combining metabolic surgery and GLP-1 medications as powerful treatments for obesity. These therapies offer significant weight loss benefits, with GLP-1 medications typically leading to a 10% reduction in body weight in real-world settings. On the other hand, metabolic surgery can result in more substantial weight loss, ranging from 25% to 30%. This combined approach not only addresses obesity but also improves overall health outcomes by reducing related conditions such as diabetes and heart disease. Metabolic surgery, including procedures like gastric bypass or sleeve gastrectomy, works by restricting food intake and altering the digestive system to promote weight loss. These surgeries are particularly effective for individuals with severe obesity, often leading to rapid and sustained weight reduction. GLP-1 medications, on the other hand, function by mimicking the body's natural hormones to suppress appetite and slow digestion, helping patients feel full and reduce calorie intake. The combination of these therapies can be especially beneficial for those who have struggled with weight loss through traditional methods or medications alone. While surgery offers more dramatic results, GLP-1 medications provide a less invasive option that is easier to access. For individuals considering these treatments, it’s crucial to consult healthcare professionals to determine the most appropriate approach based on their specific health needs. This research underscores the importance of
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Originally published on Medical Xpress on 2/20/2026