What is ALS, the disease that killed actor Eric Dane? - AP News
AP News
February 20, 2026
AI-Generated Deep Dive Summary
Amyotrophic Lateral Sclerosis (ALS), commonly known as Lou Gehrig’s disease, is a rare and incurable neurodegenerative disorder that affects nerve cells in the brain and spinal cord, leading to muscle weakness, paralysis, and ultimately, respiratory failure. The passing of actor Eric Dane, best known for his role in "House," has brought renewed attention to this devastating condition, highlighting its impact on individuals and their families.
ALS is characterized by the progressive degeneration of motor neurons, which are responsible for controlling voluntary muscles. Early symptoms often include muscle weakness, twitching, and difficulty with movement. As the disease progresses, it can lead to paralysis and challenges in speaking, eating, and breathing. While the exact cause remains unknown, research points to a combination of genetic and environmental factors contributing to its development.
Approximately 5% of ALS cases are hereditary, while the majority occur sporadically without a known family history. The average life expectancy from diagnosis is around three to five years, though some individuals live longer with supportive care. There is currently no cure for ALS, but treatments like Riluzole and Edaravone can help manage symptoms and slow disease progression.
The significance of Eric Dane’s story lies in its potential to raise awareness about ALS and inspire action. His openness about his battle with the disease has encouraged others to learn more about it and support research efforts aimed at finding a cure. By sharing his journey, he joins a legacy of notable figures, including Stephen Hawking and Lou Gehrig, who have brought attention to ALS, fostering hope and solidarity among those affected by the disease.
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Originally published on AP News on 2/20/2026