Worsening of overactive bladder seen in patients undergoing gender-affirming vaginoplasty
Medical Xpress
February 20, 2026
AI-Generated Deep Dive Summary
A recent study published in Urology reveals that individuals undergoing gender-affirming vaginoplasty may experience a deterioration in overactive bladder (OAB) symptoms, which negatively impacts their health-related quality of life (HRQoL). The research highlights that while the surgery is often sought for its psychological and social benefits, patients should be aware of potential urinary complications post-surgery. This finding underscores the importance of comprehensive pre- and post-operative care to address both mental health and physical well-being.
The study assessed 108 individuals before and after their vaginoplasty procedures, focusing on changes in OAB symptoms such as urgency, frequency, and leakage. Results showed that over half of the participants reported worsening urinary symptoms, particularly issues with urgency and incontinence. These findings suggest that the anatomical and functional changes from surgery can interfere with normal bladder function, leading to challenges in managing daily life.
Understanding the implications of these findings is crucial for anyone considering or undergoing gender-affirming surgery. The study emphasizes the need for open dialogue between patients and healthcare providers about potential risks and how to mitigate them. By addressing OAB concerns early, individuals can maintain a better quality of life while pursuing their gender-affirming journey.
This research also sheds light on the broader implications of medical interventions in transgender care. While gender-affirming surgeries are essential for many, they often come with unexpected physical side effects that require attention. The study calls for further investigation into the mechanisms behind post-surgical urinary changes and potential strategies to prevent or manage them effectively.
For readers interested in health, this study highlights the importance of holistic approaches to medical care. It demonstrates how seemingly unrelated aspects of health—such as bladder function—can be impacted by major surgeries, even those aimed at improving mental health and identity. As more individuals pursue gender-affirming procedures, understanding these potential side effects is essential for ensuring comprehensive patient care.
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Originally published on Medical Xpress on 2/20/2026